About ThermoMutDB 2.0

ThermoMutDB 2.0 represents a significant update to the protein thermodynamic stability database, designed to overcome the limitations of manual curation. This new version introduces a modernized infrastructure and a semi-automated curation ecosystem that utilizes NLP and LLM-based classifiers to identify candidate publications, which then undergo rigorous human verification to ensure high data quality.

Publications

  • ThermoMutDB (v1) — Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D475–D479.
  • ThermoMutDB 2.0 Preprint Preprint coming soon.

New data since v1

+100Articles (PMIDs) +8.6%
+516Single mutations +7.3%
+113Multiple mutations +6.8%
+141Proteins +30.0%
+895New experiments in DB +6.7%

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